Filler treatments works by adding volume to the skin and other facial structures into which it is injected. The hyaluronic acid in the formula is present in the body in nearly identical form already, so Restylane/Juvederm are completely biocompatible with the tissue that it is meant to supplement. The extra volume added by the injections can plump and smooth creased skin or change outward facial contours, depending on how the gel is applied.